Can I run with osteoarthritis?When you are diagnosed with osteoarthritis, a lot changes for you. Together with your doctor, a treatment plan will be drawn up and we will see what is and what is not possible for you. Below, we give you more information on whether you can run with osteo-arthritis. What is osteoarthritis? Osteoarthritis is a rheumatic condition in which cartilage deteriorates and becomes softer and thinner. It can occur in all joints, but is relatively more common in the thumb, neck, fingers, knees, lower back and big toe. With osteoarthritis, you experience pain, difficulty moving and stiffness.